The NAB shape learning subtest as a predictor of lateralized seizure onset

Epilepsy Behav. 2012 May;24(1):59-64. doi: 10.1016/j.yebeh.2012.02.021. Epub 2012 Apr 5.


This study presents the first empirical evaluation of the predictive value of the Neuropsychological Assessment Battery Shape Learning (NAB-SL) subtest in a sample of patients with unilateral temporal lobe epilepsy. Stimulus characteristics of the NAB-SL may improve predictive ability over other commonly used visual memory tests. Forty-nine patients with unilateral temporal lobe epilepsy were compared on measures of non-verbal and verbal memory (NAB-SL and Wechsler Memory Scale-III subtests). Univariate and forward conditional logistic regressions identified predictive values for each memory test individually and in combination. The NAB-SL delayed memory demonstrated consistently stronger predictive power over visual reproduction at the univariate and multivariate levels. The NAB-SL was a good predictor (80% range) of lateralized seizure onset when combined with a verbal memory measure. These preliminary results provide support for the use of the NAB-SL in preoperative epilepsy evaluations as a predictor of non-dominant temporal lobe dysfunction. Potential benefits of this test are discussed.

MeSH terms

  • Adult
  • Association Learning / physiology*
  • Electroencephalography
  • Epilepsy, Temporal Lobe / diagnosis*
  • Epilepsy, Temporal Lobe / psychology
  • Female
  • Functional Laterality*
  • Humans
  • Longitudinal Studies
  • Male
  • Memory / physiology*
  • Middle Aged
  • Neuropsychological Tests*
  • Photic Stimulation
  • Predictive Value of Tests
  • Verbal Learning
  • Video Recording
  • Young Adult