Two double heterozygotes in a South African Afrikaner family: implications for BRCA1 and BRCA2 predictive testing

Clin Genet. 2012 Dec;82(6):599-600. doi: 10.1111/j.1399-0004.2012.01878.x. Epub 2012 Apr 9.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • BRCA1 Protein / genetics*
  • BRCA2 Protein / genetics*
  • Breast Neoplasms / genetics*
  • Breast Neoplasms, Male / genetics*
  • DNA Mutational Analysis
  • Ethnicity / genetics*
  • Female
  • Founder Effect
  • Genetic Testing / methods*
  • Heterozygote*
  • Humans
  • Male
  • Pedigree
  • South Africa

Substances

  • BRCA1 Protein
  • BRCA2 Protein