Association between lymphoepithelial cysts of the pancreas and HIV infection

Pancreatology. 2012 Jan-Feb;12(1):61-4. doi: 10.1016/j.pan.2011.12.002. Epub 2011 Dec 8.


Background & aims: To report the association of lymphoepithelial cysts (LEC) of the pancreas with Human Immunodeficiency Virus (HIV) infection. An association between LEC and HIV infection is already established in the parotid gland (PG).

Methods: Report of the first two cases of LEC of the pancreas associated with HIV infection and comparison of the clinical and histopathological aspects of LECs of the pancreas and of the PG.

Results: LECs of the pancreas were discovered by CT imaging in 2 patients with a history of HIV infection. Notably, LEC completely resolved in one patient after initiation of antiretroviral therapy.

Conclusion: This is the first report of an association of LEC of the pancreas and HIV infection. In the presence of LEC of the pancreas, we propose a systematic screening for HIV infection and associated lesions in the PG. Antiretroviral therapy should be initiated in untreated patients. Surgery should be reserved for symptomatic patients in whom medical therapy has failed.

Publication types

  • Case Reports

MeSH terms

  • Anti-Retroviral Agents / therapeutic use
  • Epidermal Cyst / pathology
  • HIV Infections / complications*
  • Humans
  • Male
  • Middle Aged
  • Pancreatic Cyst / drug therapy
  • Pancreatic Cyst / etiology
  • Pancreatic Cyst / pathology*
  • Parotid Diseases / pathology


  • Anti-Retroviral Agents