DNA origami gatekeepers for solid-state nanopores

Angew Chem Int Ed Engl. 2012 May 14;51(20):4864-7. doi: 10.1002/anie.201200688. Epub 2012 Apr 4.


DNA has it covered: DNA origami gatekeeper nanoplates convert nanopores in solid-state membranes into versatile devices for label-free macromolecular sensing applications. The custom apertures in the nanoplates can be chemically addressed for sequence-specific detection of DNA.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / chemistry*
  • DNA, Single-Stranded / chemistry
  • Nanopores*
  • Nanostructures / chemistry*
  • Nucleic Acid Conformation


  • DNA, Single-Stranded
  • DNA