Effects of chewing gum on stress and health: a replication and investigation of dose-response

Stress Health. 2013 Apr;29(2):172-4. doi: 10.1002/smi.2430. Epub 2012 Apr 11.


Research suggests that chewing gum may be associated with reduced stress, depression and a reduced likelihood of having high cholesterol and blood pressure. The present study aimed to replicate these findings and extend them by examining dose-response. A web-based survey was completed by a sample of 388 workers from public sector organisations (68.5% female; mean age: 42 years, range 17-64 years). The results showed that chewing gum was associated in a linear dose-response manner with lower levels of perceived stress (both at work and life in general), anxiety and depression. Occasional gum chewers also reported a reduced risk of high cholesterol and blood pressure. Intervention studies are now required to extend these findings, and the mechanisms underlying the effects reported here need further investigation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Chewing Gum / statistics & numerical data*
  • Depression / epidemiology
  • Dose-Response Relationship, Drug
  • Female
  • Health Surveys
  • Humans
  • Hypertension / epidemiology
  • Male
  • Mastication / physiology*
  • Middle Aged
  • Psychiatric Status Rating Scales
  • Stress, Psychological / epidemiology*
  • Stress, Psychological / prevention & control
  • Young Adult


  • Chewing Gum