Preliminary studies on antipyretic and analgesic properties of Taverniera abyssinica

Ethiop Med J. 1990 Oct;28(4):155-61.


In an attempt to ascertain the pharmacological basis of the use of the marketed traditional drug Taverniera abyssinica A. Rich. (Amharic name Dingetegna), crude extracts as well as purified substances of this plant were tested for their antipyretic and analgesic properties. Antipyretic activity was determined on rats made hyperthermic by yeast injection and analgesic activity was determined by the hot plate, as well as the acetic acid induced writhing, methods. The study showed that the plant possesses significant antipyretic and analgesic activities.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Drug Evaluation, Preclinical
  • Ethiopia
  • Fabaceae*
  • Fever / drug therapy*
  • Isoflavones / chemistry
  • Isoflavones / pharmacology
  • Isoflavones / therapeutic use
  • Mice
  • Pain / drug therapy*
  • Plants, Medicinal / analysis*
  • Rats
  • Rats, Inbred Strains


  • Isoflavones
  • formononetin