Cyclosporine-A in the treatment of serpiginous choroiditis

Int Ophthalmol. 1990 Oct;14(5-6):395-9. doi: 10.1007/BF00163565.


Seven patients affected by bilateral inflammatory serpiginous choroiditis have been treated with Cyclosporine-A for 6-21 months. Nine out of the fourteen eyes showed a significant improvement in their visual acuity; five eyes did not change. Cyclosporine-A may, therefore, be considered effective in the treatment of this disease. Its usefulness seems to be greater when the serpiginous choroiditis is in its 'acute' stage; 'chronic' stages, however, also seem to improve under treatment. Its main indication is, in our opinion, the involvement of the macular region of the 'second' eye, when the 'first' eye is already damaged. We consider Cyclosporine-A, in these situations, to be a first choice treatment.

MeSH terms

  • Choroiditis / drug therapy*
  • Clinical Trials as Topic
  • Cyclosporins / therapeutic use*
  • Follow-Up Studies
  • Humans
  • Visual Acuity / drug effects


  • Cyclosporins