Factors leading to excessive polypharmacy

Clin Geriatr Med. 2012 May;28(2):159-72. doi: 10.1016/j.cger.2012.01.001. Epub 2012 Feb 15.

Abstract

There are numerous risk factors for patients to develop excessive polypharmacy. The most prominent risk factors are associated with sociodemographics and the patients’ conditions. Risk factors associated with patient behavior, such as patient’s self medication with all types of medications, have not been observed to the same extent but might be at the same level of importance for patients developing excessive polypharmacy. Risk factors related to physicians, and the interaction between patient and physician, are studied to a much lesser extent. The few studies conducted regarding the large variation in physicians’ individual prescribing practices, in terms of polypharmacy, add another perspective to the complexity of the area. Interventions aiming to improve communication between GP and hospital specialist, to create support systems for medical reviews that include all patients’ medications, and to improve the knowledge of multiple prescribing might have the largest potential to better manage excessive polypharmacy.

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Attitude of Health Personnel
  • Attitude to Health
  • Drug-Related Side Effects and Adverse Reactions
  • Female
  • Health Behavior
  • Health Status
  • Humans
  • Inappropriate Prescribing
  • Male
  • Middle Aged
  • Pharmaceutical Preparations / administration & dosage*
  • Polypharmacy*
  • Practice Patterns, Physicians'*
  • Risk Factors
  • Self Medication*
  • Socioeconomic Factors

Substances

  • Pharmaceutical Preparations