ABO blood group and risk of pancreatic cancer in a Turkish population in Western Blacksea region

Asian Pac J Cancer Prev. 2012;13(1):131-3.


Background: We aimed to investigate the relationship between blood groups and pancreatic cancer in a Turkish population in Western Blacksea region.

Methods: This is a retrospective study. Zonguldak Karaelmas University outpatient oncology clinic records were screened for the period between 2004 and 2011.

Results: The median age of patients were 56 (± 16) and 132 of 633 study population had pancreatic cancer. Pancreatic cancer patients had significantly higher rates of blood group A compared to controls (OR 1.8, 95%CI, p 0.005). Rates of blood group AB was significantly lower than the control group (OR 0.37, 95% CI, p 0.04). The median survival (IR) time in subjects having the blood groups A, B, AB and O were 7.0 (1-28), 7.0 (2-38), 10 (2-36) and 9.0 (2-48) months respectively; the blood group 0 had significantly higher overall survival (OS) compared to the non-0 groups (p 0.04).

Conclusions: Pancreatic cancer patients had more common blood group A in our population. Moreover, blood group AB appeared to be a protective factor against pancreatic cancer in our population. Blood group 0 had a significantly longer survival compared to non-0, regardless of prognostic factors.

Publication types

  • Comparative Study

MeSH terms

  • ABO Blood-Group System*
  • Case-Control Studies
  • Disease Susceptibility
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pancreatic Neoplasms / epidemiology
  • Pancreatic Neoplasms / etiology*
  • Pancreatic Neoplasms / mortality*
  • Pancreatic Neoplasms / prevention & control
  • Prognosis
  • Retrospective Studies
  • Risk Assessment
  • Surveys and Questionnaires
  • Survival Rate
  • Turkey / epidemiology


  • ABO Blood-Group System