Amnesic disorders

Lancet. 2012 Oct 20;380(9851):1429-40. doi: 10.1016/S0140-6736(11)61304-4. Epub 2012 Apr 13.


Memory disturbances frequently occur after brain damage, but can be associated with psychiatric illnesses as well. Amnesia--the most severe form of memory impairment--has several variants, including anterograde and retrograde amnesia, material-specific and modality-specific amnesia, and transient global amnesia. We searched databases to obtain an overview of amnesia research from the past 5 years. Research into amnesia has increased exponentially, probably because of the availability of modern brain-imaging techniques. In line with the view that memory is not a unity but is organised into several systems, amnesia is described as a multifaceted disease with a frequently poor prognosis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amnesia* / classification
  • Amnesia* / etiology
  • Amnesia* / genetics
  • Amnesia* / physiopathology
  • Animals
  • Brain / physiopathology
  • Humans
  • Memory / physiology
  • Prognosis