Prospective Risk of Stillbirth: Monochorionic Diamniotic Twins vs. Dichorionic Twins

J Perinat Med. 2012 Jan 10;40(3):245-9. doi: 10.1515/jpm-2011-0205.

Abstract

Aims: To determine reliably the risk of stillbirth among twin pregnancies.

Methods: A data analysis of 3241 and 6581 women with monochorionic diamniotic (MD) and dichorionic (DD) twins, respectively, who gave birth at ≥22 weeks of gestation.

Results: The prospective risk (per 1000 women) of stillbirth, 25.3 and 11.5 at gestational week 22, decreased to <10.0 at gestational weeks 31 and 28 among the MD and DD twins, respectively. After single intrauterine fetal death, the co-twin died in utero or within 7 days of life more frequently among MD twins than among DD twins [42.7% (35/82) vs. 2.6% (2/76); relative risk, 16.2; 95% confidence interval, 4.0-65.1].

Conclusion: Women with MD twins were 2.2-fold more likely to experience stillbirth than women with DD twins. The prospective risks of stillbirth were <1.0% for both groups of women at ≥32 weeks of gestation.

Publication types

  • Twin Study

MeSH terms

  • Amnion / anatomy & histology
  • Chorion / anatomy & histology
  • Diseases in Twins / mortality
  • Female
  • Fetal Death / epidemiology
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Japan / epidemiology
  • Male
  • Perinatal Mortality
  • Pregnancy
  • Pregnancy, Twin*
  • Prospective Studies
  • Retrospective Studies
  • Risk Factors
  • Stillbirth / epidemiology*
  • Twins, Dizygotic*
  • Twins, Monozygotic*