Piperacillin/tazobactam Induced Myelosuppression

J Clin Med Res. 2009 Apr;1(1):53-5. doi: 10.4021/jocmr2009.03.1227. Epub 2009 Mar 24.


Neutropenia, secondary to immune destruction or maturation arrest, is the most commonly described adverse haematological effect of beta-lactam antibiotics. We describe a case of reversible pancytopenia, with evidence of hypocellular marrow, after a prolonged course of piperacillin/tazobactam for 26 days.

Keywords: Piperacillin; Tazobactam; Myelosuppression; Neutropenia.

Publication types

  • Case Reports