A non-photochemical approach to the bicyclo[3.2.0]heptane core of bielschowskysin

Org Lett. 2012 May 4;14(9):2195-7. doi: 10.1021/ol3006419. Epub 2012 Apr 16.

Abstract

An asymmetric synthesis of the tricyclic core (-)-1 of the marine diterpene bielschowskysin is described. In particular, a methodology was developed to introduce the crucial quaternary center at C-12.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diterpenes / chemical synthesis*
  • Diterpenes / chemistry*
  • Heptanes / chemistry
  • Molecular Structure
  • Stereoisomerism

Substances

  • Diterpenes
  • Heptanes
  • bielschowskysin