Comparison of the anaesthetic efficacy of and heart rate changes after periodontal ligament or intraosseous X-Tip injection in mandibular molars: a randomized controlled clinical trial

Int Endod J. 2012 Oct;45(10):921-6. doi: 10.1111/j.1365-2591.2012.02050.x. Epub 2012 Apr 16.

Abstract

Aim: To compare the efficacy of supplemental anaesthesia using periodontal ligament injections (PDL) and intraosseous injections with the X-Tip system in terms of the measured heart rate and patient reported pain level.

Methodology: In this single-blind randomized clinical trial, 40 patients (22 women, 18 men) with irreversible pulpitis who had experienced unsuccessful pain management by inferior alveolar nerve block with 2% lidocaine and 1 : 100 000 epinephrine were selected. Patients were divided equally and randomly into two groups. Supplementary anaesthesia was provided through intraosseous injection with the X-Tip system (X-Tip group) or by PDL injection (PDL group). After each step of injection, pain severity was assessed using a visual analogue scale. Patient heart rate was recorded with a pulse oximeter. Data were coded and analysed using Mann-Whitney U-test with SPSS (version 16) software.

Results: Anaesthetic success was obtained in 100% of X-Tip and 70% of PDL group patients after the first supplemental injection. Compared with the first PDL injection, the first intraosseous injection resulted in a significant increase in heart rate (P = 0.001); however, this increase was short-lived (mean increase: 9-10 beats per min). No significant difference in heart rate or anaesthesia success was observed between men and women.

Conclusion: Intraosseous injection using the X-Tip system was more effective than PDL injection as a supplementary anaesthetic for pulpectomy in mandibular molars or second premolars. However, the former resulted in a transient increase in heart rate.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anesthesia, Dental / instrumentation*
  • Anesthetics, Local / administration & dosage*
  • Bone and Bones
  • Female
  • Heart Rate / drug effects*
  • Humans
  • Infusions, Intraosseous / instrumentation*
  • Injections / instrumentation*
  • Lidocaine / administration & dosage
  • Male
  • Mandible
  • Mandibular Nerve
  • Middle Aged
  • Molar
  • Nerve Block / instrumentation*
  • Pain Measurement
  • Periodontal Ligament
  • Pulpectomy*
  • Pulpitis / surgery
  • Single-Blind Method
  • Statistics, Nonparametric
  • Young Adult

Substances

  • Anesthetics, Local
  • Lidocaine