Antioxidant function of vitamin A

Int J Vitam Nutr Res. 1977;47(4):394-401.


Feeding of 100 000 I.U. of Vitamin A on alternate days, five times to rats, resulted in a marked lowering in in vitro lipid peroxidation of the tissue hemogenates. alpha-Tocopherol or DPPD supplementation along with A still further reduced the in vitro lipid peroxidation of the tissues. Vitamin A in large doses increased the antioxygenic potential of the tissues, and it is suggested that retinol also might be considered as a potential antioxidant similar to tocopherol in animal nutrition.

MeSH terms

  • Alopecia / chemically induced
  • Animal Nutritional Physiological Phenomena
  • Animals
  • Erythrocytes / metabolism
  • Hydrogen-Ion Concentration
  • Lipid Metabolism*
  • Lipids / blood
  • Oxidation-Reduction / drug effects*
  • Phenylenediamines / pharmacology
  • Posture
  • Rats
  • Vitamin A / administration & dosage
  • Vitamin A / pharmacology*
  • Vitamin E / pharmacology


  • Lipids
  • Phenylenediamines
  • Vitamin A
  • Vitamin E