Diagnostic yield of small bowel capsule endoscopy depends on the small bowel transit time

World J Gastroenterol. 2012 Apr 7;18(13):1502-7. doi: 10.3748/wjg.v18.i13.1502.


Aim: To investigate whether the small bowel transit time (SBTT) influences the diagnostic yield of capsule endoscopy (CE).

Methods: Six hundred and ninety-one consecutive CE procedures collected in a database were analyzed. SBTT and CE findings were recorded. A running mean for the SBTT was calculated and correlated to the diagnostic yield with a Spearman's correlation test. Subgroup analyses were performed for the various indications for the procedure.

Results: There was a positive correlation between the diagnostic yield and SBTT (Spearman's rho 0.58, P < 0.01). Positive correlations between diagnostic yield and SBTT were found for the indication obscure gastrointestinal bleeding (r = 0.54, P < 0.01), for polyposis and carcinoid combined (r = 0.56, P < 0.01) and for the other indications (r = 0.90, P <0.01), but not for suspected Crohn's disease (r = -0.40).

Conclusion: The diagnostic yield in small bowel capsule endoscopy is positively correlated with the small bowel transit time. This is true for all indications except for suspected Crohn's disease.

Keywords: Capsule endoscopy; Diagnostic yield; Small bowel transit time.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Capsule Endoscopy / methods*
  • Gastrointestinal Transit / physiology*
  • Humans
  • Intestinal Diseases / diagnosis*
  • Intestine, Small / pathology*
  • Intestine, Small / physiology*
  • Time Factors