Meningovascular form of neuroborreliosis: similarities between neuropathological findings in a case of Lyme disease and those occurring in tertiary neurosyphilis

Acta Neuropathol. 1990;80(5):568-72. doi: 10.1007/BF00294622.


Recent observations have delineated the neurological manifestations of Lyme disease, but, to our knowledge, no detailed neuropathological study from autopsy cases has been reported. In this report we describe the neuropathological findings in a case of Lyme neuroborreliosis. The chronic meningitis, the occlusive meningovascular and secondary parenchymal changes that we found are similar to those occurring in the meningovascular form of neurosyphilis. Thus, we suggest that the case described here represents the meningovascular form of tertiary Lyme neuroborreliosis.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Humans
  • Immunohistochemistry
  • Lyme Disease / pathology*
  • Male
  • Meninges / blood supply*
  • Meninges / pathology*
  • Middle Aged
  • Neurosyphilis / pathology*