EBUS-TBNA in patients presented with superior vena cava syndrome

Lung Cancer. 2012 Aug;77(2):277-80. doi: 10.1016/j.lungcan.2012.03.015. Epub 2012 Apr 20.


Introduction: Expedient pathological diagnosis is crucial in selection of appropriate treatment in patients presented with superior vena cava syndrome (SVCS). The performance and safety of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in this setting is unknown.

Methods: Over a 4-year period, patients presented with SVCS in the presence of mediastinal mass and referred for EBUS-TBNA were enrolled for the study. The procedure was performed under local anaesthesia with conscious sedation. TBNA was performed under real-time with the curvilinear probe of EBUS. Rapid on site cytological examination (ROSE) was not available.

Results: Eighteen procedures of EBUS-TBNA were performed in 17 patients. Malignancy was confirmed in 16 patients (diagnostic yield 94.1%). There was no major complication including significant bleeding or pneumothorax related to the procedures.

Conclusions: EBUS-TBNA has high diagnostic yield and is safe in patients presented with SVCS and mediastinal mass.

MeSH terms

  • Aged
  • Biopsy, Needle
  • Bronchi / pathology*
  • Bronchoscopy / methods
  • Female
  • Humans
  • Male
  • Middle Aged
  • Superior Vena Cava Syndrome / diagnosis*
  • Superior Vena Cava Syndrome / pathology
  • Ultrasonography, Interventional / adverse effects
  • Ultrasonography, Interventional / methods*