Solar radiation and vitamin D: mitigating environmental factors in autoimmune disease

J Environ Public Health. 2012;2012:619381. doi: 10.1155/2012/619381. Epub 2012 Jan 11.

Abstract

This paper looks at the environmental role of vitamin D and solar radiation as risk reduction factors in autoimmune disease. Five diseases are considered: multiple sclerosis, type 1 diabetes, rheumatoid arthritis, autoimmune disease of the thyroid, and inflammatory bowel disease. Clinical relevant studies and factors that may indicate evidence that autoimmune disease is a vitamin D-sensitive disease are presented. Studies that have resulted in prevention or amelioration of some autoimmune disease are discussed. An example of the utility of supplementing vitamin D in an unusual autoimmune disease, idiopathic thrombocytic purpura, is presented.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Autoimmune Diseases / etiology
  • Autoimmune Diseases / therapy*
  • Female
  • Humans
  • Middle Aged
  • Purpura, Thrombocytopenic, Idiopathic / etiology
  • Purpura, Thrombocytopenic, Idiopathic / therapy*
  • Treatment Outcome
  • Ultraviolet Rays*
  • Vitamin D / therapeutic use*

Substances

  • Vitamin D