Poly(3-hydroxyalkanoate)-derived amphiphilic graft copolymers for the design of polymersomes

Julien Babinot; Jean-Michel Guigner; Estelle Renard; Valérie Langlois

doi:10.1039/c2cc30482a

Poly(3-hydroxyalkanoate)-derived amphiphilic graft copolymers for the design of polymersomes

Chem Commun (Camb). 2012 May 28;48(43):5364-6. doi: 10.1039/c2cc30482a. Epub 2012 Apr 23.

Authors

Julien Babinot¹, Jean-Michel Guigner, Estelle Renard, Valérie Langlois

Affiliation

¹ Institut de Chimie et des Matériaux Paris-Est (ICMPE), Systèmes Polymères Complexes, UMR CNRS 7182, 2-8 rue Henri Dunant, 94320 Thiais, France.

PMID: 22525424
DOI: 10.1039/c2cc30482a

Abstract

Amphiphilic graft copolymers composed of biocompatible bacterial poly(3-hydroxyalkanoate) and poly(ethylene glycol) have been synthesized by thiol-ene addition. They were demonstrated to form well-defined nanoscale vesicles in water by cryo-transmission electron microscopy.

MeSH terms

Biocompatible Materials / chemical synthesis
Biocompatible Materials / chemistry*
Cryoelectron Microscopy
Nanotechnology
Polyethylene Glycols / chemistry
Polymers / chemical synthesis*
Polymers / chemistry
Water / chemistry

Substances

Biocompatible Materials
Polymers
Water
Polyethylene Glycols