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Randomized Controlled Trial
. 2012 Apr;52(2):170-4.

Effect of Methylsulfonylmethane Supplementation on Exercise - Induced Muscle Damage and Total Antioxidant Capacity

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  • PMID: 22525653
Randomized Controlled Trial

Effect of Methylsulfonylmethane Supplementation on Exercise - Induced Muscle Damage and Total Antioxidant Capacity

S Barmaki et al. J Sports Med Phys Fitness. .

Abstract

Aim: The aim of this study was to evaluate effect of 10-day methylsulfonylmethane (MSM) supplementation on exercise-induced muscle damage.

Methods: Eighteen healthy, non-smoking, active young men were recruited to participate in this study. Participants were randomized in a double-blind placebo-controlled fashion into two groups: MSM (M) (N.=9) and placebo (P) (N.=9). Subjects consumed daily either placebo (200 mL water) or MSM supplement (50 mg/kg MSM in 200 mL water) for 10 days. Afterward, participants ran 14 km. Blood samples were taken before supplementation, before exercise, immediately, 30 min, 2, 24 and 48 h after exercise.

Results: CK and bilirubin significantly increased in P group 24 h after exercise compared to M group (P=0.041 and P=0.002, respectively). TAC increased immediately post, 30 min, 2 and 24 h after exercise just in M group (P<0.05). TAC showed significant increase in M group 2 and 24 h after exercise compared to P group (P=0.014 and P=0.033, respectively).

Conclusion: It seems that 10-day supplementation with MSM has allowed to decrease muscle damage via effect on antioxidant capacity.

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