Malignant Melanoma in Transplant Patients: A Case Report and Review of the Literature

Cutis. 2012 Mar;89(3):133-6.

Abstract

The clinical course and outcome of malignant melanoma (MM) are well-established for immunocompetent groups; however, they are not well-documented for immunosuppressed populations. Specifically, the influence of immunosuppression may result in poorer outcomes, especially in more advanced cases of melanoma. We report a 67-year-old woman who had previously undergone a kidney and pancreas transplant and presented with American Joint Committee on Cancer (AJCC) stage IIIA melanoma with subsequent rapid demise. As medicine advances with greater numbers of organ transplant recipients, a multi-institutional prospective study for this at-risk population would be greatly beneficial to help characterize the incidence, progression, and prognosis of melanoma in posttransplant immunosuppressed populations.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Diabetes Mellitus
  • Diagnosis, Differential
  • Female
  • Forearm
  • Humans
  • Kidney Transplantation*
  • Melanoma / diagnosis*
  • Melanoma / etiology
  • Melanoma / pathology
  • Melanoma / surgery
  • Neoplasm Staging
  • Renal Insufficiency
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / etiology
  • Skin Neoplasms / pathology
  • Skin Neoplasms / surgery