"DNA traffic lights": concept of wavelength-shifting DNA probes and application in an aptasensor

Chembiochem. 2012 May 29;13(8):1136-8. doi: 10.1002/cbic.201200117. Epub 2012 Apr 25.

Abstract

Add it and see it: The concept of "DNA traffic lights" for wavelength-shifting DNA probes has a great potential in the application of biosensors, for example, in DNA aptamers. A visual color change in the DNA aptasensor fluorescence from green to red occurs after specific target binding.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Aptamers, Nucleotide / chemistry*
  • Aptamers, Nucleotide / genetics
  • Base Sequence
  • Biosensing Techniques
  • DNA / chemistry*
  • DNA / genetics
  • DNA Probes / chemistry*
  • DNA Probes / genetics
  • Fluorescent Dyes / chemistry*
  • Molecular Sequence Data
  • Oligonucleotides / chemistry
  • Spectrometry, Fluorescence / methods

Substances

  • Aptamers, Nucleotide
  • DNA Probes
  • Fluorescent Dyes
  • Oligonucleotides
  • DNA