Direct His bundle and paraHisian cardiac pacing

Ann Noninvasive Electrocardiol. 2012 Apr;17(2):70-8. doi: 10.1111/j.1542-474X.2012.00488.x.


The success rate of direct His bundle pacing (DHBP) and paraHisian pacing has improved remarkably in the last 3-5 years with the advent of dedicated fixation systems that have reduced procedural duration, dislodgement rate, and fluoroscopy time. The methodology of DBHP remains still more complex than paraHisian pacing and is associated with high-pacing thresholds. Thus, DHBP entails greater battery current drain and reduced device longevity. A shift toward paraHisian pacing (which is fusion pacing of myocardium and His bundle) has occurred because its implementation is easier and the electrical parameters are superior to those of DBHP. Currently, an additional safety lead is inserted at the RV apex or outflow tract to prevent asystole, especially in patients with pure DHBP. It is often possible to avoid a safety lead with paraHisian pacing because ventricular pacing is virtually assured on a long-term basis via myocardial capture. DBHP and paraHisian pacing can be achieved in a substantial proportion of patients with varying grades of narrow QRS AV block or after AV junctional ablation and in some patients with the ECG manifestation of bundle branch block caused by an intraHisian lesion. Preliminary observations suggest that DHBP may be useful in some patients requiring cardiac resynchronization if it produces a narrow QRS complex because the site of an intraHisian lesion responsible for left bundle branch block is above the site of DHBP.

Publication types

  • Review

MeSH terms

  • Bundle of His / physiopathology*
  • Bundle-Branch Block / physiopathology*
  • Bundle-Branch Block / therapy*
  • Cardiac Pacing, Artificial / methods*
  • Electrocardiography
  • Fluoroscopy
  • Hemodynamics
  • Humans
  • Pacemaker, Artificial*