Fatal pneumonitis induced by oxaliplatin: description of three cases

Case Rep Oncol. 2012 Jan;5(1):104-9. doi: 10.1159/000337030. Epub 2012 Feb 29.

Abstract

We describe 3 fatal cases of interstitial pneumonitis rapidly evolving to pulmonary fibrosis and death after the administration of oxaliplatin as part of the FOLFOX regimen. Due to the widespread use of oxaliplatin in oncology, clinicians should be aware of the risk and severity of oxalipatin-induced interstitial pneumonia.

Keywords: Drug-induced toxicities; FOLFOX7m; Interstitial pneumonia; Oxaliplatin.

Publication types

  • Case Reports