Medication-related problems occurring in people with diabetes during an admission to an adult teaching hospital: a retrospective cohort study

Diabetes Res Clin Pract. 2012 Aug;97(2):223-30. doi: 10.1016/j.diabres.2012.03.003. Epub 2012 Apr 26.


Aims: To examine the characteristics of medication-related problems occurring in people with diabetes admitted to hospital and to identify risk factors for medication-related problems.

Methods: A retrospective cohort study of medication-related problems occurring in patients admitted to an adult, inner-city Australian teaching hospital was conducted over two-years. The risk factors associated with medication-related problems were identified using random effect logistic regression.

Results: There were 9530 admissions of people with diabetes involving 5205 individuals over a two-year period. Medication-related problems were associated with 686 (7.2%) admissions involving 571 individuals (11.0%). The most common medication-related problems were medication errors (64.1%) associated with hypoglycaemia and unintentional overdose. Five factors were significantly associated with medication-related problems: female gender [odds ratio (OR) 1.30, 95% confidence intervals (CI) 1.11-1.52], age of 18-50 years (OR 2.32, CI 1.85-2.91), single marital status (OR 1.46, CI 1.24-1.74), mental and behavioural problems (OR 1.74, 1.43-2.11), and a comorbidity index score of at least one (OR 1.35-1.67).

Conclusions: Five significant risk factors were associated with medication-related problems in people with diabetes admitted to hospital. These risks need to be considered when developing care plans and interventions to prevent medication-related problems for individuals with diabetes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Australia / epidemiology
  • Cohort Studies
  • Comorbidity
  • Diabetes Mellitus, Type 1 / drug therapy
  • Diabetes Mellitus, Type 1 / economics
  • Diabetes Mellitus, Type 1 / epidemiology*
  • Diabetes Mellitus, Type 2 / drug therapy
  • Diabetes Mellitus, Type 2 / economics
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Female
  • Hospitalization
  • Hospitals, Teaching
  • Humans
  • Hypoglycemia / chemically induced
  • Hypoglycemia / economics
  • Hypoglycemia / epidemiology*
  • Logistic Models
  • Male
  • Medication Errors / statistics & numerical data*
  • Middle Aged
  • Patient Compliance*
  • Prescription Drug Misuse*
  • Retrospective Studies
  • Risk Factors
  • Young Adult