Ocular melanoma in families with dysplastic nevus syndrome

J Am Acad Dermatol. 1990 Nov;23(5 Pt 1):858-62. doi: 10.1016/0190-9622(90)70304-z.


Five families with the dysplastic nevus syndrome, in each of which one member had ocular melanoma, are reported. These five families were examined within a 3-year period in one medical center. To date only five other families with such a combination have been reported. We suggest a causal relation between ocular melanoma and the familial dysplastic nevus syndrome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Dysplastic Nevus Syndrome / genetics*
  • Eye Neoplasms / genetics*
  • Female
  • Humans
  • Male
  • Melanoma / genetics*
  • Middle Aged
  • Neoplasms, Multiple Primary / genetics*
  • Skin Neoplasms / complications
  • Skin Neoplasms / genetics