Comparing the effects of ginger and metoclopramide on the treatment of pregnancy nausea

Pak J Biol Sci. 2011 Aug 15;14(16):817-20. doi: 10.3923/pjbs.2011.817.820.


This study assesses the effects of ginger on nausea and vomiting caused by pregnancy and compares it with metoclopramide medicine. This study was a randomized double-blind controlled trial. Metoclopramide, Ginger and placebo were putted in similar capsules. The medicines were administered three times a day. Then the Rhodes questionnaire was completed and its score were calculated. Data were analyzed by Chi square test, ANOVA and Repeated measurement. The intensity of changes in nausea, vomiting and Rhodes during study were statistically different in two groups of ginger and metoclopramide compared with placebo (p < 0.05), but it was not statistically significant between two groups of ginger and metoclopramide. According to our study, ginger is less effective than metoclopramide in reducing nausea and vomiting but it could be a good alternative for metoclopramide.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antiemetics / therapeutic use*
  • Double-Blind Method
  • Female
  • Humans
  • Metoclopramide / therapeutic use*
  • Nausea / drug therapy*
  • Placebos
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Treatment Outcome
  • Vomiting / drug therapy*
  • Young Adult
  • Zingiber officinale*


  • Antiemetics
  • Placebos
  • Metoclopramide