Galectins testing: new promises for the diagnosis and risk stratification of chronic diseases?

Clin Biochem. 2012 Jul;45(10-11):719-26. doi: 10.1016/j.clinbiochem.2012.04.009. Epub 2012 Apr 24.


Galectins are carbohydrate binding proteins involved in several biological functions such as intracellular signaling, cell to cell interaction and exchanges between cells and the extracellular matrix. Galectins are therefore participating to the control of gene expression, the regulation of immune response and the control of cell growth and viability. Galectins have stimulated in one hand a great interest for their potent contribution to the physiopathology of several diseases and cancers and may represent in another hand relevant biomarkers to support the diagnosis and prognosis of several disorders.

Publication types

  • Review

MeSH terms

  • Biomarkers / analysis*
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / metabolism*
  • Chronic Disease
  • Galectin 1 / analysis
  • Galectin 3 / analysis
  • Galectins / analysis*
  • Humans
  • Neoplasms / diagnosis
  • Neoplasms / metabolism*
  • Predictive Value of Tests
  • Risk Factors


  • Biomarkers
  • Galectin 1
  • Galectin 3
  • Galectins