New conduction abnormalities after TAVI--frequency and causes

Nat Rev Cardiol. 2012 May 1;9(8):454-63. doi: 10.1038/nrcardio.2012.58.


Transcatheter aortic valve implantation (TAVI) is increasingly used to treat patients with aortic stenosis who are considered to be too high-risk for surgical replacement of the aortic valve. Although the procedural risks are decreasing, the occurrence of new conduction abnormalities remains a vexing issue. Both left bundle branch block and atrioventricular dissociation can affect prognosis after TAVI. Understanding the intimate relationship between the atrioventricular conduction axis and the aortic root, in addition to elucidation of factors related specifically to the procedure, devices, and patients, might help to reduce these conduction abnormalities. The purpose of this Review is to assess, and offer insights into, the available information on the frequency of new conduction abnormalities associated with TAVI, their anatomical and procedural causes, and their clinical consequences.

Publication types

  • Review

MeSH terms

  • Aortic Valve / pathology*
  • Aortic Valve / surgery
  • Aortic Valve Stenosis / surgery*
  • Arrhythmias, Cardiac / etiology*
  • Arrhythmias, Cardiac / pathology
  • Bundle-Branch Block
  • Heart Conduction System / pathology*
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / methods*
  • Humans
  • Prognosis
  • Risk