Copper-catalyzed oxidative cyclization of enynes for the synthesis of 4-carbonyl-quinolines with O2

Org Lett. 2012 May 18;14(10):2480-3. doi: 10.1021/ol300896h. Epub 2012 May 2.

Abstract

A novel copper-catalyzed oxidative cyclization of enynes and in situ formed enynes leading to 4-carbonyl-quinolines by using dioxygen as an oxygen source has been developed.