Repo-Man-PP1: a link between chromatin remodelling and nuclear envelope reassembly

Nucleus. 2012 Mar 1;3(2):138-42. doi: 10.4161/nucl.19267. Epub 2012 Mar 1.


Coordination of late mitotic events is crucial for the maintenance of genome stability and for the control of gene expression after cell division. Reversible protein phosphorylation regulates this process by de-phosphorylation of mitotic phospho-proteins in a sequential and coordinated manner: this allows an orderly sequence of events to take place during mitotic exit. We have identified Repo-Man/PP1 as a phosphatase complex that regulates temporally and spatially chromatin re-organization and nuclear envelope re-formation during anaphase-telophase.

Publication types

  • Review

MeSH terms

  • Anaphase
  • Chromatin Assembly and Disassembly*
  • Nuclear Envelope / metabolism*
  • Nuclear Proteins / metabolism*
  • Protein Phosphatase 1 / metabolism*
  • Telophase


  • Nuclear Proteins
  • Protein Phosphatase 1