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. 2012 Jul;22(7):1068-76.
doi: 10.1007/s11695-012-0654-8.

Bone mineral changes in spine and proximal femur in individual obese women after laparoscopic sleeve gastrectomy: a short-term study

Wojciech Pluskiewicz  1 , Marek Bužga, Pavol Holéczy, Ladislav Bortlík, Vít Šmajstrla, Piotr Adamczyk
Affiliations

Bone mineral changes in spine and proximal femur in individual obese women after laparoscopic sleeve gastrectomy: a short-term study

Wojciech Pluskiewicz et al. Obes Surg. 2012 Jul.

Abstract

Background: The aim of the study was to establish longitudinal bone changes in obese women after laparoscopic sleeve gastrectomy (LSG).

Methods: Twenty-nine women at baseline mean age of 40.41 ± 9.26 years and with mean body mass index (BMI) of 43.07 ± 4.99 kg/m(2) were included in a 6-month study. Skeletal status at hip [femoral neck (FN) and total hip (TH)] and spine was assessed at baseline, as well as in 3 and 6 months after surgery. Body size was measured at baseline and follow-up (weight, height, BMI, and waist).

Results: Baseline body weight was 117.5 ± 18.4 kg. The mean body weight and BMI decreased by 17.9 % during the first 3 months after surgery to obtain 28.4 % after 6 months. At 6 months, BMD decreased significantly for spine by 1.24 %, FN 6.99 %, and TH 5.18 %. The changes after 3 months in individual subjects showed that, in the majority of subjects, FN and TH BMD decreased significantly (in 52 % and 69 % of subjects, respectively), and in 24 % loss of BMD was found at the spine. After 6 months, the corresponding, significant decreases in individual subjects were found in 72 %, 86 %, and 38 % of woman, respectively. Those with a significant loss of FN BMD tended to lose more weight (30 ± 9.47 versus 23.25 ± 6.08 kg, p = 0.061) than others; women with a significant decrease of FN BMD lost more weight than those with no such decrease (30.43 ± 8.07 versus 15 ± 1.91 kg).

Conclusion: LSG proved efficient for body weight reduction, however, with a parallel decline in bone mineral density.

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Figures

Fig. 1
Fig. 1
Individual values of excess body weight (expressed as percentage of ideal weight) during the period of observation
Fig. 2
Fig. 2
Longitudinal BMD change for lumbar spine during the first 3 months of observation in individual patients. LS BMD lumbar spine bone mineral density, LSC least significant change
Fig. 3
Fig. 3
Longitudinal BMD change for femoral neck during the first 3 months of observation in individual patients. FN BMD femoral neck bone mineral density, LSC least significant change
Fig. 4
Fig. 4
Longitudinal BMD change for total hip during the first 3 months of observation in individual patients. TH BMD total hip bone mineral density, LSC least significant change
Fig. 5
Fig. 5
Longitudinal BMD change for lumbar spine during 6 months of observation in individual patients. LS BMD lumbar spine bone mineral density, LSC least significant change
Fig. 6
Fig. 6
Longitudinal BMD change for femoral neck during 6 months of observation in individual patients. FN BMD femoral neck bone mineral density, LSC least significant change
Fig. 7
Fig. 7
Longitudinal BMD change for total hip during 6 months of observation in individual patients. TH BMD total hip bone mineral density, LSC least significant change
Fig. 8
Fig. 8
Individual values of BMD for total hip during the period of observation. BMD bone mineral density
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