Analysis of factors correlated with the development of pseudophakic retinal detachment--a long-term study in a single medical center

Graefes Arch Clin Exp Ophthalmol. 2013 Feb;251(2):459-65. doi: 10.1007/s00417-012-2043-3. Epub 2012 May 5.


Background: To analyze the possible factors correlated with the development of retinal detachment (RD) after cataract extraction and intraocular lens (IOL) implantation in a single medical center.

Methods: We performed a retrospective chart review of patients receiving cataract extraction and posterior chamber IOL implantation from January 2000 to June 2010 at one medical center. We analyzed demographic characteristics, medical history, axial length (AL), operation method, intraoperative and postoperative complications, Nd-YAG posterior capsulotomy and records for RD.

Results: The 9,184 patients analyzed included 6,464 males and 2,720 females, mean age 71.8 ± 9.1 years. The cumulative 7-year RD rate was 0.84 %. Young age, long axial length and intraoperative complications were significantly associated with the risk of pseudophakic RD. Although not a statistically significant factor for the whole group, Nd-YAG posterior capsulotomy represented a significant risk in those with high myopia stratified by axial length. In moderate myopic group, both intra-operative complication and Nd-YAG posterior capsulotomy showed more tendencies to increase risk of RD, but only intra-operative complication had significant difference.

Conclusions: Young age, myopia and intra-operative complications were significant risk factors for the development of RD after cataract extraction and IOL implantation. Post-operative Nd-YAG posterior capsulotomy led to more risk for pseudophakic RD in myopic eyes, especially high myopia. The risk of pseudophakic RD should be considered before deciding to perform cataract extraction and the following capsulotomy in myopic eyes, particularly those for refractive indication in young patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Axial Length, Eye / pathology
  • Capsule Opacification / surgery
  • Cataract Extraction*
  • Female
  • Follow-Up Studies
  • Humans
  • Intraoperative Complications
  • Laser Therapy
  • Lasers, Solid-State
  • Lens Implantation, Intraocular*
  • Male
  • Middle Aged
  • Myopia / complications
  • Postoperative Complications*
  • Pseudophakia / etiology*
  • Retinal Detachment / etiology*
  • Retrospective Studies
  • Risk Factors
  • Young Adult