Developmental dyslexia: dysfunction of a left hemisphere reading network

Front Hum Neurosci. 2012 May 1;6:120. doi: 10.3389/fnhum.2012.00120. eCollection 2012.


This mini-review summarizes and integrates findings from recent meta-analyses and original neuroimaging studies on functional brain abnormalities in dyslexic readers. Surprisingly, there is little empirical support for the standard neuroanatomical model of developmental dyslexia, which localizes the primary phonological decoding deficit in left temporo-parietal (TP) regions. Rather, recent evidence points to a dysfunction of a left hemisphere reading network, which includes occipito-temporal (OT), inferior frontal, and inferior parietal regions.

Keywords: brain; developmental dyslexia; fMRI; meta-analysis; neuroimaging; reading.