Management of dermatitis herpetiformis

Immunol Allergy Clin North Am. 2012 May;32(2):275-81, vi-vii. doi: 10.1016/j.iac.2012.04.007. Epub 2012 Apr 18.

Abstract

The major treatment strategies for DH are gluten restriction or medical treatment with sulfones. Control of the cutaneous manifestations, but not the gastrointestinal changes, is rapid with dapsone. In addition to control of the cutaneous signs and symptoms of DH, dietary gluten restriction also induces improvement of gastrointestinal morphology and is possibly protective against the development of lymphoma.

Publication types

  • Review

MeSH terms

  • Animals
  • Autoantibodies / immunology
  • Autoantigens / immunology*
  • Celiac Disease / immunology
  • Celiac Disease / therapy*
  • Dapsone / therapeutic use
  • Dermatitis Herpetiformis / immunology
  • Dermatitis Herpetiformis / therapy*
  • Diet, Gluten-Free
  • Humans
  • Immunoglobulin A / immunology
  • Leprostatic Agents / therapeutic use
  • Mouth Mucosa / pathology
  • Skin / immunology
  • Skin / pathology
  • Transglutaminases / immunology*

Substances

  • Autoantibodies
  • Autoantigens
  • Immunoglobulin A
  • Leprostatic Agents
  • Dapsone
  • TGM3 protein, human
  • Transglutaminases