Abstract
Dapsone is used in the treatment of autoimmune bullous diseases (AIBD), a group of disorders resulting from autoimmunity directed against basement membrane and/or intercellular adhesion molecules on cutaneous and mucosal surfaces. This review summarizes the limited published data evaluating dapsone as a therapy for AIBD.
Copyright © 2012 Elsevier Inc. All rights reserved.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Agranulocytosis / etiology
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Animals
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Autoimmune Diseases / drug therapy*
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Autoimmune Diseases / immunology
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Dapsone / adverse effects
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Dapsone / chemistry
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Dapsone / therapeutic use*
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Disease Management
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Drug Hypersensitivity / etiology
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Humans
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Leprostatic Agents / therapeutic use*
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Methemoglobinemia / etiology
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Neutrophil Activation / drug effects
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Neutrophils / drug effects
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Neutrophils / immunology
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Skin Diseases, Vesiculobullous / drug therapy*
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Skin Diseases, Vesiculobullous / immunology
Substances
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Leprostatic Agents
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Dapsone