Safety essentials: acute reactions to iodinated contrast media

Can Assoc Radiol J. 2013 Aug;64(3):193-9. doi: 10.1016/j.carj.2011.12.014. Epub 2012 May 5.


The objectives of this article are to review the diagnosis and management of acute nonrenal reactions to iodinated contrast media. We will begin by discussing the types of contrast media and their correlative rates of reaction. The mechanism of contrast reactions, predisposing risk factors, and preventative measures will then be discussed. The remainder of the article will review the assessment of potential reactions, initial management, and treatment algorithms for specific reactions.

Keywords: Acute reactions; Iodinated contrast.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Adult
  • Child
  • Contrast Media / adverse effects*
  • Drug Hypersensitivity / drug therapy
  • Drug Hypersensitivity / etiology*
  • Drug Hypersensitivity / prevention & control
  • Humans
  • Injections, Intravenous
  • Iodine Compounds / adverse effects*
  • Risk Factors
  • Safety*


  • Contrast Media
  • Iodine Compounds