An outbreak of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit

Infect Control Hosp Epidemiol. 2012 Jun;33(6):631-4. doi: 10.1086/665715. Epub 2012 Apr 16.

Abstract

We present a large outbreak of ESBL-producing Klebsiella pneumoniae in a neonatal intensive care unit that resulted in 31 colonized infants, 10 invasive infections, and 5 attributable deaths over a 5-month period. Although the source of infection was unknown, overcrowding and understaffing appeared to have been aggravating factors.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Biomarkers / metabolism
  • Cross Infection / epidemiology*
  • Cross Infection / prevention & control
  • Disease Outbreaks* / prevention & control
  • Humans
  • Infant, Newborn
  • Infection Control
  • Intensive Care Units, Neonatal*
  • Klebsiella Infections / epidemiology*
  • Klebsiella Infections / prevention & control
  • Klebsiella pneumoniae* / drug effects
  • Klebsiella pneumoniae* / isolation & purification
  • Klebsiella pneumoniae* / metabolism
  • Microbial Sensitivity Tests
  • beta-Lactam Resistance*
  • beta-Lactamases / metabolism*

Substances

  • Biomarkers
  • beta-Lactamases