[Chronic juvenile arthritis with serum antinuclear antibodies. Study of 136 cases]

Arch Fr Pediatr. 1990 Aug-Sep;47(7):497-502.
[Article in French]


The charts of 136 patients presenting with juvenile chronic arthritis and antinuclear antibodies were reviewed. Mean age at onset was 3.6 yrs and 120 patients were females. Twenty-one patients presented with the polyarticular type of the disease from onset. Among them, 3 had polyarthritis with presence of rheumatoid factors. During the first year of follow-up, 40% of the pauciarticular forms became polyarticular. They may be subdivided into extended pauciarticular (5 to 9 arthritis = 26% of cases) or polyarticular (greater than 9 arthritis = 15% of cases) forms. The ocular involvement, present in 50 patients, preceded the articular manifestations in 5 cases (for a maximum of 4 years) whereas it followed in 30 cases (maximum delay of 14 years). Inflammatory articular involvement is not always correlated with the risk of ocular involvement. Long-term articular prognosis is generally fair. Only 15 children present with clearcut functional handicaps, of whom 4 are requiring the help of a third person.

Publication types

  • English Abstract

MeSH terms

  • Antibodies, Antinuclear / analysis*
  • Arthritis, Juvenile / complications
  • Arthritis, Juvenile / diagnosis
  • Arthritis, Juvenile / immunology*
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Humans
  • Iridocyclitis / etiology
  • Male
  • Prognosis
  • Uveitis, Anterior / etiology


  • Antibodies, Antinuclear