Contact sensitivity to metals (chromium, cobalt and nickel) in childhood

An Bras Dermatol. 2012 Mar-Apr;87(2):269-76. doi: 10.1590/s0365-05962012000200012.

Abstract

Metals, especially nickel, are the most common contact allergens in children. Recent data has shown increased incidence of allergy in industrialized countries. Sensitization can occur at any age, even in neonates. Costume jewelry, particularly earrings, is linked to increased sensitization to nickel. Sensitization to cobalt often occurs by the use of costume jewelry. The most common source of sensitization to chromium is leather. Due to the absence of a specific therapy, the main treatment is to identify and avoid the responsible allergens. This article presents an updated view on the epidemiological and clinical aspects of contact allergy to metals, focusing on prevention strategies and risk factors, and warns about possible and new sources of contact.

Publication types

  • Review

MeSH terms

  • Child
  • Chromium / adverse effects*
  • Cobalt / adverse effects*
  • Dermatitis, Allergic Contact* / diagnosis
  • Dermatitis, Allergic Contact* / epidemiology
  • Dermatitis, Allergic Contact* / therapy
  • Histamine Antagonists / therapeutic use
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Nickel / adverse effects*
  • Risk Factors

Substances

  • Histamine Antagonists
  • Immunosuppressive Agents
  • Chromium
  • Cobalt
  • Nickel