GPSy: a cross-species gene prioritization system for conserved biological processes--application in male gamete development

Nucleic Acids Res. 2012 Jul;40(Web Server issue):W458-65. doi: 10.1093/nar/gks380. Epub 2012 May 8.


We present gene prioritization system (GPSy), a cross-species gene prioritization system that facilitates the arduous but critical task of prioritizing genes for follow-up functional analyses. GPSy's modular design with regard to species, data sets and scoring strategies enables users to formulate queries in a highly flexible manner. Currently, the system encompasses 20 topics related to conserved biological processes including male gamete development discussed in this article. The web server-based tool is freely available at

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Caenorhabditis elegans / genetics
  • Caenorhabditis elegans / physiology
  • Gene Expression
  • Genes*
  • Genomics / methods
  • Internet
  • Male
  • Models, Animal
  • Molecular Sequence Annotation
  • RNA Interference
  • Software*
  • Spermatogenesis / genetics*