Necrobiotic xanthogranuloma: response to chlorambucil

Australas J Dermatol. 2012 May;53(2):e23-5. doi: 10.1111/j.1440-0960.2010.00710.x. Epub 2010 Oct 20.

Abstract

This report of necrobiotic xanthogranuloma associated with chronic lymphocytic leukaemia describes the response of skin lesions to chlorambucil. Characteristic clinical and histological features of necrobiotic xanthogranuloma are presented, as well as a discussion regarding management and the use of chlorambucil.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents, Alkylating / therapeutic use*
  • Chlorambucil / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Necrobiotic Xanthogranuloma / drug therapy*
  • Necrobiotic Xanthogranuloma / pathology

Substances

  • Antineoplastic Agents, Alkylating
  • Chlorambucil