[Obesity, body fat distribution and the incidence of breast, cervical, endometrial and ovarian carcinomas]

Dtsch Med Wochenschr. 1990 Dec 14;115(50):1906-10. doi: 10.1055/s-2008-1065242.
[Article in German]

Abstract

The connection of body fat distribution (BFD) and the risk of developing mammary, cervical, endometrial or ovarian carcinoma was ascertained for 163 patients with carcinoma (mean age 49.9 [19-78] years) and 489 controls of comparable age and body-mass index. BFD was expressed as the ratio of waist and hip circumference (T/H ratio of 0.822 vs 0.781 and 0.826 vs 0.789, respectively; P less than 0.01). In premenopausal women with mammary or cervical carcinoma and in all postmenopausal women BFD was similar to that in the control subjects. A common cause of android obesity and ovarian or endometrial carcinoma may be a reduction of sex-hormone-binding globulins with an elevated serum level of free androgens and oestrogens.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Body Mass Index*
  • Breast Neoplasms / epidemiology*
  • Female
  • Germany / epidemiology
  • Humans
  • Incidence
  • Menopause
  • Middle Aged
  • Obesity / epidemiology*
  • Ovarian Neoplasms / epidemiology*
  • Risk Factors
  • Uterine Cervical Neoplasms / epidemiology*
  • Uterine Neoplasms / epidemiology*