Long-term hepatic safety of ambrisentan in patients with pulmonary arterial hypertension

MeSH terms

• Adult
• Aged
• Alanine Transaminase / blood
• Antihypertensive Agents / administration & dosage*
• Antihypertensive Agents / adverse effects*
• Aspartate Aminotransferases / blood
• Chemical and Drug Induced Liver Injury / enzymology
• Chemical and Drug Induced Liver Injury / epidemiology
• Chemical and Drug Induced Liver Injury / etiology*
• Drug Administration Schedule
• Endothelin A Receptor Antagonists*
• Endothelins / antagonists & inhibitors
• Female
• Humans
• Hypertension, Pulmonary / drug therapy*
• Incidence
• Liver / drug effects*
• Liver / enzymology
• Liver / pathology
• Liver / physiopathology
• Liver Function Tests
• Male
• Middle Aged
• Phenylpropionates / administration & dosage*
• Phenylpropionates / adverse effects*
• Pyridazines / administration & dosage*
• Pyridazines / adverse effects*
• Risk Factors
• United States / epidemiology