Higher magnification lenses versus conventional lenses for evaluation of diabetic neuropathy by corneal in vivo confocal microscopy

Diabetes Res Clin Pract. 2012 Aug;97(2):e37-40. doi: 10.1016/j.diabres.2012.04.010. Epub 2012 May 10.

Abstract

We tested agreement for small fibre morphology using corneal in vivo confocal microscopy between the recently available higher-magnification 300 μm(2) and the conventional 400 μm(2) field-of-view lenses. We found insignificant bias for corneal nerve fibre length indicating that either lens could reasonably be applied to research and clinical screening for diabetic neuropathy.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Cornea / pathology*
  • Cornea / physiopathology
  • Diabetes Mellitus, Type 1 / pathology*
  • Diabetic Neuropathies / pathology*
  • Diabetic Neuropathies / physiopathology
  • Female
  • Humans
  • Male
  • Microscopy, Confocal / instrumentation
  • Microscopy, Confocal / methods*
  • Nerve Fibers / pathology*
  • Reproducibility of Results