Effects of mesenchymal stem cells isolated from amniotic fluid and platelet-rich plasma gel on severe decubitus ulcers in a septic neonatal foal

Res Vet Sci. 2012 Dec;93(3):1439-40. doi: 10.1016/j.rvsc.2012.04.008. Epub 2012 May 9.

Abstract

This paper documents the treatment of severe decubitus ulcers with amniotic fluid mesenchymal stem cells and platelets rich plasma (PRP) gel in a septic neonatal foal. The colt needed 25 days of hospitalization: during this period ulcers were treated for 15 days with mesenchymal stem cells (MSCs) plus PRP, PRP gel alone, or aloe gel. Healing was faster using MSCs+PRP, and at 7 months an ulcer treated with aloe gel was still not completely healed.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn
  • Gels
  • Horse Diseases / therapy*
  • Horses
  • Male
  • Mesenchymal Stem Cell Transplantation / veterinary*
  • Platelet-Rich Plasma*
  • Pressure Ulcer / complications
  • Pressure Ulcer / therapy
  • Pressure Ulcer / veterinary*
  • Sepsis / complications
  • Sepsis / veterinary*
  • Time Factors
  • Wound Healing / drug effects

Substances

  • Gels