[Lacrimal dysfunction and pregnancy]

Rev Bras Ginecol Obstet. 2012 Apr;34(4):170-4. doi: 10.1590/s0100-72032012000400006.
[Article in Portuguese]


Purpose: To assess the prevalence of lacrimal dysfunction during pregnancy comparing it to non-pregnant women and to correlate these findings with obstetric history.

Methods: We interviewed 150 pregnant and 150 non-pregnant women for symptoms of dry eyes and obstetric history. Both groups underwent Schirmer I testing and responded to a questionnaire on dry eye symptoms. Patients with collagen diseases, medications associated with dryness of mucous membranes, hepatitis C infection and AIDS, previous intraocular inflammation and eye surgery were excluded. Data were analyzed by the Χ2 and Fisher tests when the data were nominal and by the Student´s t-test and Mann-Whitney test when numerical. The level of significance was set at 5%.

Results: The two groups did not differ in symptoms of lacrimal dysfunction. The results of Schirmer's test were equal in both groups for the right eye (p=0.3) and left eye (p=0.3). However, pregnant women had a higher prevalence of at least one dry eye (p=0.004). The occurrence of dry eye in both groups (patients and controls) was associated with a greater number of full-term pregnancies/patient (p=0.04) but not with pregnancy time (p=0.5) or number of abortions (p=0.9).

Conclusions: Pregnant women suffer more from lacrimal dysfunction than non pregnant women; in both groups the prevalence of tear dysfunction is more elevated in women with higher parity.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Case-Control Studies
  • Cross-Sectional Studies
  • Dry Eye Syndromes / epidemiology*
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Prevalence