New cis-regulatory elements in the Rht-D1b locus region of wheat

Funct Integr Genomics. 2012 Aug;12(3):489-500. doi: 10.1007/s10142-012-0283-2. Epub 2012 May 17.


Fifteen gene-containing BACs with accumulated length of 1.82-Mb from the Rht-D1b locus region were sequenced and compared in detail with the orthologous regions of rice, sorghum, and maize. Our results show that Rht-D1b represents a conserved genomic region as implied by high gene sequence identity, good maintenance of gene colinearity, and the presence of multiple conserved noncoding sequences (CNSs) that are shared by other grass species. Eight cis-regulatory elements in these CNSs around grass DELLA genes were detected.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Chromosomes, Artificial, Bacterial / genetics
  • Chromosomes, Plant / genetics
  • Conserved Sequence
  • DNA Transposable Elements
  • Gene Order
  • Genes, Duplicate
  • Genes, Plant*
  • Genetic Loci*
  • Molecular Sequence Annotation
  • Molecular Sequence Data
  • Oryza / classification
  • Oryza / genetics
  • Plant Proteins / genetics
  • Regulatory Sequences, Nucleic Acid*
  • Sequence Alignment
  • Sorghum / genetics
  • Synteny
  • Triticum / genetics*
  • Triticum / growth & development


  • DNA Transposable Elements
  • Plant Proteins
  • RHT-D1A protein, Triticum aestivum