[Correlations between clusters of protein-DNA binding sites and the binding experimental data allow to predict a structure of regulatory modules]

Biofizika. Mar-Apr 2012;57(2):212-4.
[Article in Russian]

Abstract

Here we analyzed an option to predict the structure of cis-regulatory modules that consist of binding sites of different proteins (heterogeneous cis-regulatory modules) using mutual positional correlations between protein-DNA binding experimental data and computationally identified clusters of binding sites for each of the proteins.

Publication types

  • English Abstract
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • DNA-Binding Proteins / genetics*
  • DNA-Binding Proteins / metabolism
  • Drosophila Proteins / genetics*
  • Drosophila Proteins / metabolism
  • Drosophila melanogaster
  • Response Elements / physiology*

Substances

  • DNA-Binding Proteins
  • Drosophila Proteins